Cancer Research UK has a list of current trials for triple negative breast cancer. Clinical trialsĬlinical trials are trying to find out if different treatments will be helpful in treating triple negative breast cancer. Some breast cancer treatments, such as hormone (endocrine) therapy and HER2 targeted therapies are of no benefit to people with triple negative breast cancer. The drugs used are likely to include carboplatin or cisplatin. Chemotherapy for triple negative breast cancer is often given before surgery. Research has shown chemotherapy generally has a larger benefit for triple negative breast cancer compared to oestrogen receptor positive breast cancer. Triple negative breast cancer can be treated with a combination of If this is appropriate in your situation, your treatment team will discuss this with you. Women who are over the age of 50 may also be referred to a specialist genetics clinic to discuss genetic testing. Women who are under the age of 50 when they are diagnosed with triple negative breast cancer should be offered a referral to a specialist family history clinic or a regional genetics clinic to discuss genetic testing, regardless of their family history of breast cancer. Women with triple negative breast cancer are more likely to have an altered BRCA1 gene than women with oestrogen receptor positive breast cancer. Find out more about coping with worries about breast cancer coming back. However, after around five years the risks are similar to, and may be lower than, other types of breast cancer. Research has shown that the risk of triple negative breast cancer coming back or spreading is higher than some types of breast cancer in the first few years. ![]() However, most people with triple negative breast cancer have invasive ductal breast cancer as this is the most common type of breast cancer in general. These include medullary and metaplastic breast cancer. Some types of breast cancer are more likely to be triple negative than others. women who have not yet reached the menopause.women who have inherited an altered BRCA gene (particularly BRCA1).Triple negative breast cancer is more common in: How common is triple negative breast cancer?ġ5% of all breast cancers – over 8,000 cases a year in the UK – are triple negative. If your cancer doesn’t have oestrogen and progesterone receptors and is HER2 negative, you have triple negative breast cancer. If breast cancer cells have a normal level of HER2 on their surface, they’re known as HER2 negative (HER2-). Invasive breast cancers are tested for HER2 levels using tissue from a biopsy or surgery. Some breast cancer cells have a higher than normal level of a protein called HER2 on their surface, which stimulates them to grow. If it doesn’t have progesterone receptors, it’s called progesterone receptor negative (PR -).įind out more about hormone receptors and breast cancer. If breast cancer doesn’t have oestrogen receptors, it’s called oestrogen receptor negative (ER -). Tests will also be done to see if your breast cancer is progesterone receptor positive (PR+). Invasive breast cancers are tested to see if they are ER+ using tissue from a biopsy or after surgery. This type of breast cancer is called oestrogen receptor positive (ER+). This means that oestrogen in the body helps the cancer to grow. Some breast cancers are stimulated by the hormone oestrogen. Triple negative breast cancer is the name given to breast cancer that is: ![]() How common is triple negative breast cancer?ĥ. Download a printable version of this information about triple negative breast cancer »ġ.
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